Enhanced detection of circulating tumor DNA by fragment size analysis
نویسندگان
چکیده
منابع مشابه
Fragment Length of Circulating Tumor DNA
Malignant tumors shed DNA into the circulation. The transient half-life of circulating tumor DNA (ctDNA) may afford the opportunity to diagnose, monitor recurrence, and evaluate response to therapy solely through a non-invasive blood draw. However, detecting ctDNA against the normally occurring background of cell-free DNA derived from healthy cells has proven challenging, particularly in non-me...
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ژورنال
عنوان ژورنال: Science Translational Medicine
سال: 2018
ISSN: 1946-6234,1946-6242
DOI: 10.1126/scitranslmed.aat4921